GWAS summary data tables
Skotte L et al. Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes. Brain 2022; doi: 10.1093/brain/awab260
The file include results for approximately 6.8 million (MAF>1%) directly genotyped or imputed variants to the Phase 3 release of the 1000 Genomes Project reference panel. Logistic regression was used to test for differences in allele dosage between cases and controls under an additive genetic model.
Dataset details
The summary statistics file contains results from GWAS discovery analysis of febrile seizures (n=4502) versus controls (n=51049). The file provides information on chromosome, genomic position (NCBI build 37), rsID, effect allele, other allele, odds ratio for the effect allele, standard error, and P value, at approximately 6.8 million variants passing quality control.
Acknowledging the data
When using data from the downloadable meta-analyses results please acknowledge the source of the data as follows:
Data on febrile seizures has been contributed by Statens Serum Institut researchers and has been downloaded from https://www.danishnationalbiobank.com/GWAS.
In addition to the above acknowledgement, please cite the paper below:
Skotte L et al. Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes. Brain 2022; doi: 10.1093/brain/awab260.
Downloading the data
https://biobanks.dk/GWAS/Skotte2022_Febrile_Seizures.txt.gz
Disclaimer
These data are provided "as is" and without warranty, for scientific and educational use only. The authors assume no responsibility for errors or omissions. If you download these data, you acknowledge that these data will be used only for non-commercial research purposes; that the investigator is in compliance with all laws or regulations and institutional policies regarding human subjects and genetics research; and that secondary distribution of the data is prohibited. The authors shall not be held liable for any use or misuse of the data.