GWAS summary data tables

Provided are SAIGE results for the five hernia groups inguinal, diaphragmatic, umbilical, femoral, ventral and the two combined groups any hernia and any hernia excluding diaphragmatic. Covariates were sex (only in the all analyses), year of birth and the first six principal components calculated for the analyzed subset of the UK Biobank with British ancestry. Provided are the results for the full cohort (all) and the subgroups of females and males.

Variables in the datasets

• CHR – chromosome
• POS – position in bp (build 37)
• SNPID - variant
• Allele1 – non-effect allele
• Allele2 – effect allele
• AFAllele2 – frequency of effect allele
• BETA –effect estimate for effect allele
• padj – p-value for variant, adjusted for genomic control

Acknowledging the data

When using data from the downloadable GWAS scans please acknowledge the source of the data as follows:

GWAS data on hernia has been downloaded from https://www.danishnationalbiobank.com/GWAS.

In addition to the above acknowledgement, please cite our paper:

Fadista J et al. Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci. https://www.nature.com/articles/s41467-022-30921-4.

Downloading the data

Disclaimer

These data are provided "as is" and without warranty, for scientific and educational use only. The authors assume no responsibility for errors or omissions. If you download these data, you acknowledge that these data will be used only for non-commercial research purposes; that the investigator is in compliance with all laws or regulations and institutional policies regarding human subjects and genetics research; and that secondary distribution of the data is prohibited. The authors shall not be held liable for any use or misuse of the data.